NU 606 Week 3 Discussion 1 Question-Based Discussion
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NU 606 Week 3 Discussion 1 Question-Based Discussion
Paper Instructions
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Team C Infection
- Explain why a person whose blood test shows an abnormally low leukocyte count should be given an antimicrobial drug before a tooth extraction. Give one example of a condition where this prophylaxis would be indicated.
- Explain how routine laboratory tests might not show the presence of mycoplasma, rickettsia, or protozoans in the body. How are these microbes best detected?
- Compare the prodromal period with the acute period of infection, using your own experience as an example (perhaps the last time you had a cold).
- List three local signs of infection and three systemic signs; explain what is causing these signs. Are these objective or subjective findings?
- Describe two mechanisms by which antibacterial drugs act on microorganisms. Explain the benefit of narrow-spectrum over broad-spectrum drugs.
- Explain why secondary bacterial infection is common in persons with influenza. Which secondary infections are most common?
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Sample Answer
Describe two mechanisms by which antibacterial drugs act on microorganisms. Explain the benefit of narrow-spectrum over broad-spectrum drugs.
Antibacterial drugs act on microorganisms by using a variety of methods to destroy the pathogen. Some of the the various methods include the method of the drug to attack the wall or thick coating surrounding the bacteria – this allows it to penetrate inside the cell and kill it off that way.
Another method is through interfering with the reproduction of the bacterial cell and lastly, the medication can assist in blocking protein production. According to the International Society of Antimicrobial Chemotherapy, the main differences that separate narrow and broad-spectrum drugs from each other are that “narrow-spectrum antibiotics are active against a select group of bacterial types.
Broad-spectrum antibiotics are active against a wider number of bacterial types and, thus, may be used to treat a variety of infectious diseases” (ISAC, 2021). Broad-spectrum antibiotics tend to be our tried and true methods that most providers tend to turn towards. In short, this means that broad-spectrum antibiotics are more versatile when it comes to treating multi-infections or different strains of bacteria.
Some broad-spectrum antibiotics are things like doxycycline, amoxicillin, and ampicillin. On the other hand, you have narrow-spectrum drugs that are only active against specified strains of bacteria. More specifically, narrow-spectrum antibiotics can fight against either gram-negative or gram-positive bacteria but not both at the same time. While broad-spectrum can cover both gram-negative and gram-positive at once.
Although broad-spectrum antibiotics are effective and useful, there’s a hidden truth behind why narrow-spectrum antibiotics have some slight advantage This is because broad-spectrum antibiotics can even wipe out your healthy normal flora or bacteria in the body.
In addition, using a narrow spectrum assists in decreasing the probability of creating antibiotic-resistant bacteria. Using broad-spectrum antibiotics carelessly like when they’re not needed is the main reason why we have some of these superbugs today.
Citations
- International Society of Antimicrobial Chemotherapy. (2021). Alliance for the prudent use of antibiotics. APUA. Retrieved September 13, 2021, from https //apua.org/.
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