PUB 540 Calculating Odds Ratio

Paper Instructions

Data can be qualitative or quantitative. Qualitative data is helpful to generate a hypothesis and gather information if little is known about an expected association. Focus groups, key informant interviews, and case studies are types of qualitative data collection methods used to identify common themes from which to build a hypothesis. Quantitative data collection and analysis is used to test a hypothesis and make comparisons to determine the direction and strength of a potential association.

The Behavioral Risk Factor Surveillance System (BRFSS) is cross-sectional panel survey used to collect quantitative data on adult behaviors and risk factors. It is one of the largest U.S. health data collection efforts. The data can be used to analyze associations on a state or country level. Follow the steps to obtain a 2×2 contingency table (also known as a \”cross tabulation\”) crossing binge drinking with depression.

  • Retrieve the \”BRFSS Web-Enabled Analysis Tool\” resource provided in the Topic Materials.
  • Select \”Cross Tabulation.\”
  • Select \”2015\” for the year.
  • Select \”Arizona\” for the state.
  • Select \”Alcohol Consumption Binge drinkers (males having five or more drinks on one occasion, females having four or more drinks on one occasion)\” for Step 2 Select Row.
  • Select \”Chronic Health Conditions Ever diagnosed with a depressive disorder, including depression, major depression, dysthymia, or minor depression\” for Step 3 Select Column.
  • Skip Steps 4 and 5.
  • Select \”Sample Size\” for Step 6 Select Statistics and run the report for the cross tabulation.

Part 1

Using the data from the cross tabulation results, calculate the odds ratio for depression among those exposed to binge drinking. Interpret the odds ratio and discuss if the odds ratio is a good estimate of the relative risk in this situation. Why or why not? Show your 2×2 table and all calculations. Present or describe the formula you used to arrive at your answer.

Part 2

Use the Topic Material, \”BRFSS Web-Enabled Analysis Tool,\” located on the CDC website, and run a report for two variables of interest to you. Create a 2×2 table and calculate the odds ratio for this association. Interpret the odds ratio and discuss the public health importance of the association. Show your 2×2 table. Present or describe the formula you used to arrive at your answer.

  • Refer to the \”Creating a 2×2 Contingency Table\” resource for guidance in creating 2×2 contingency tables.

General Requirements

APA style is not required, but solid academic writing is expected.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.

Attachments

  • PUB-540-RS-Creating2x2ContingencyTable.docx

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From the above odds ratio, there is a public health importance for the association (Persoskie & Ferrer, 2017). In other words, the relationship determined can be applied in the determination of the negative consequences of binge drinking (Kilander et al., 2016). Determination of odds ratios is essential when it comes to the measurement of the association between exposure and non-exposure (Martinez et al., 2017).

In the above case, the odds ratio can be applied in the determination of the probability of depression occurring for the individuals engaged in the binge drinking (Meeks et al., 2016). From the previous case, the depression may also occur when an individual is not exposed to binge drinking.

Behavioral Risk Factor Surveillance System (BRFSS)

Calculated variable for binge drinkers, men having 5+ drinks on one occasion and women having 4+ drinks on one occasion (_RFBING5)

Statistics  Yes  No  Total
Total Sample Size  1406 5991 7397
Row % 19.2%   80.8%  100%
Column %    100%   100%
No Sample Size 1275 5441 6716
Row % 19.3%   80.7%  100%
Column %  86%  85.7%   85.8%
Total % (Weighted)  16.5% 69.2% 85.8%
Yes Sample Size 131 550  681
Row %  18.9%  81.1% 100%
Column % 14% 14.3% 14.2%
Total % (Weighted)  2.7%  11.6% 14.2%

 

  • Wald Chi-Square Value: 0.03
  • Degrees of Freedom: 1
  • p-value: 0.8553
  • Number of records on the BRFSS dataset for the year and location selected: 7946
  • Number of records excluded from the analysis: 549
  • Sample Size (Number of records used in the analysis): 7397
  • Total Weighted N (Population): 4824701

(Stare & Maucort-Boulch, 2016)

Part I

The tables show the outcomes for the cross-tabulation between binge drinkers, men having 5+ drinks on one occasion and women having 4+ drinks on one occasion and depression.

For non-binge drinkers, odds ratio is given by:

  • = p (1-p) (probability of non-drinkers binge having depression)
  • = 19.3/80.7
  • = 0.239

For binge drinkers, odds ratios is given by:

  • = p (1-p) (probability of binge drinkers having depression)
  • = 18.9/81.1
  • = 0.233

In general, the odds ratio is given by:

  • = p (1-p) (probability of binge drinkers having depression)/ p (1-p) (probability of binge drinkers having depression) (Hancock & Kent, 2016)
  • = 0.239/0.233
  • = 1.03

The odds show that individuals exposed to binge drinking are 1.03 times more likely to develop depression. In other words, those exposed to binge drinking are 3% more likely to have depression. The odds ratio is therefore a good estimate of the relative risk in this case

Part II

Calculated variable for 4 level smoker status everyday/someday/former/non-smoker (_SMOKER3) Calculated variable for ever told you had any types of cancer including skin cancer (CHCOCNCR, CHCSCNCR )

Statistics  Yes  No  Total
Total Sample Size  1773   5799  7572
Row % 13.7%   86.3% 100%
Column %    100%   100%
Total % (Weighted) 13.7% 86.3% 100%
Current smoker – every day Sample Size  47  223  270
Row % 11.9% 88.1%  100%
Column %  4.1%  4.9%  4.8%
Total % (Weighted)  0.6%   4.2%   4.8%
Former smoker Sample Size  740  1673 2413
Row %  21%  79%  100%
Column % 38.3%  22.9%  25%
Total % (Weighted)  5.2% 19.7% 25%
Never smoked Sample Size  876  3400  4276
Row %  10.9%  89.1% 100%
Column % 48.6%  63%  61%
Total % (Weighted)  6.7%  54.3% 61%

 

  • Wald Chi-Square Value: 84.59
  • Degrees of Freedom: 3
  • p-value: <0.0001

 

  • Number of records on the BRFSS dataset for the year and location selected: 7946
  • Number of records excluded from the analysis: 374
  • Sample Size (Number of records used in the analysis): 7572
  • Total Weighted N (Population): 4950718

The table above shows the cross tabulation for smokers and the possibility of developing any form of cancer.

For everyday smokers, the odds ratio for developing any form of cancer is given by:

  • = p (1-p) (every day smoker having any form of cancer) (Chang & Hoaglin, 2017)
  • = 11.9/88.1
  • = 0.134

For Current smoker – some days,

  • = p (1-p) (some day smoker having any form of cancer)
  • = 21/79
  • = 0.27

Therefore, odds ratio is given by 0.27/0.134

  • = 2.01

The above scenario shows that everyday smokers are two times more likely to develop any form of cancer including skin cancer (Katz, 2016). The public importance of the above association is that it can enhance the creation of awareness for smoking relate cancers. It can also be used in the processes of developing interventions for different types of cancers (Solmi et al., 2016).

In conclusion, there is the representation of cross-tabulation for the depression among the individuals exposed to binge drinking (Roman-Viñas et al., 2016). Odds ratios of an event occurring is defined as the probability or the likelihood that an event will occur, expresses as a percentage or as a proportion that the event will not occur (Persoskie & Ferrer, 2017).

References

  • Chang, B. H., & Hoaglin, D. C. (2017). Meta-analysis of odds ratios current good practices. Medical care, 55(4), 328. 10.1097/MLR.0000000000000696
  • Hancock, M., & Kent, P. (2016). Interpretation of dichotomous outcomes risk, odds, risk ratios, odds ratios and number needed to treat. Retrieved from www.elsevier.com/locate/jphys
  • Katz, K. A. (2016). The (relative) risks of using odds ratios. Archives of dermatology, 142(6), 761-764. Retrieved from https //jamanetwork.com/journals/jamadermatology/article-abstract/405502
  • Kilander, H., Alehagen, S., Svedlund, L., Westlund, K., Thor, J., & Brynhildsen, J. (2016). Likelihood of repeat abortion in a Swedish cohort according to the choice of post‐abortion contraception a longitudinal study. Acta obstetricia et gynecologica Scandinavica, 95(5), 565-571. Retrieved from https //obgyn.onlinelibrary.wiley.com/doi/full/10.1111/aogs.12874
  • Martinez, B. A. F., Leotti, V. B., Nunes, L. N., Machado, G., & Corbellini, L. G. (2017). Odds ratio or prevalence ratio? An overview of reported statistical methods and appropriateness of interpretations in cross-sectional studies with dichotomous outcomes in veterinary medicine. Frontiers in veterinary science, 4, 193. https //doi.org/10.3389/fvets.2017.00193
  • Meeks, K. A., Freitas-Da-Silva, D., Adeyemo, A., Beune, E. J., Modesti, P. A., Stronks, K., … & Agyemang, C. (2016). Disparities in type 2 diabetes prevalence among ethnic minority groups resident in Europe a systematic review and meta-analysis. Internal and emergency medicine, 11(3), 327-340. Retrieved from https //link.springer.com/article/10.1007%2Fs11739-015-1302-9
  • Persoskie, A., & Ferrer, R. A. (2017). A most odd ratio interpreting and describing odds ratios. American journal of preventive medicine, 52(2), 224-228. https //doi.org/10.1016/j.amepre.2016.07.030
  • Roman-Viñas, B., Chaput, J. P., Katzmarzyk, P. T., Fogelholm, M., Lambert, E. V., Maher, C., … & Tremblay, M. S. (2016). Proportion of children meeting recommendations for 24-hour movement guidelines and associations with adiposity in a 12-country study. International journal of behavioral nutrition and physical activity, 13(1), 1-10. Retrieved from https //link.springer.com/article/10.1186/s12966-016-0449-8
  • Solmi, M., Veronese, N., Sergi, G., Luchini, C., Favaro, A., Santonastaso, P., … & Stubbs, B. (2016). The association between smoking prevalence and eating disorders A systematic review and meta‐analysis. Addiction, 111(11), 1914-1922. https //doi.org/10.1111/add.13457
  • Stare, J., & Maucort-Boulch, D. (2016). Odds ratio, hazard ratio and relative risk. Metodoloski zvezki, 13(1), 59. Retrieved from https //ibmi.mf.uni-lj.si/mz/2016/no-1/p4.pdf

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